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当前位置: 首页 > 产品中心 > alkali > PBL/抗人IFNAR2抗体,克隆MMHAR-2,中和(MAb)/50μg/21385-1
商品详细PBL/抗人IFNAR2抗体,克隆MMHAR-2,中和(MAb)/50μg/21385-1
PBL/抗人IFNAR2抗体,克隆MMHAR-2,中和(MAb)/50μg/21385-1
PBL/抗人IFNAR2抗体,克隆MMHAR-2,中和(MAb)/50μg/21385-1
商品编号: 21385-1
品牌: PBL
市场价: ¥9900.00
美元价: 4950.00
产地: 美国(厂家直采)
公司:
产品分类:
公司分类: alkali
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Anti-Human IFNAR2 Antibody, Clone MMHAR-2, neutralizing (MAb)

Product Features:
  • Anti-IFNAR2 antibody (clone MMHAR-2) to human Interferon (Alpha, Beta and Omega) Receptor 2
  • Blocks the biological action of Human Type I Interferons
  • Suitable for use in Type I IFN neutralization, flow cytometry, immunohistochemistry, and immunoprecipitation

Full Product Name: Anti-Human Interferon Alpha/Beta Receptor Chain 2, Clone MMHAR-2 (MAb)

Ordering

Catalog No. Pack Size Price Quantity
21385-1

50 μg

$495.00
$575.00
  • Specifications
  • Tech Info / Data
  • Citations
  • Documentation

Specifications

FormulationSupplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
AntigenHuman interferon alpha/beta receptor chain 2 (Human IFNAR2)
IsotypeIgG2A
Host SpeciesMouse
Purity> 95% by SDS-PAGE stained by Coomassie BlueEndotoxin level < 1 EU/μg
BioactivityMeasured by neutralization of interferon in cytopathic effect inhibition assay.
SpecificityNeutralizes human IFN-alpha receptor; interacts with extracellular domain; binds to human IFN-alpha receptor with high affinity; blocks biological action of Type I IFNs
StorageFor retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Antigen SynonymsNone
CloneMMHAR-2

Tech Info / Data

Tested Applications:

  • Neutralization

Suggested Applications*:

  • Immunoprecipitation (1-5 μg/ml)
  • Immunohistochemistry (1 μg/ml)
  • Flow Cytometry (1-10 μg/ml)

*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL.

 

Background:

The Type I interferon receptor is a heterodimer consisting of IFNAR1 and IFNAR2. The IFNAR2 subunit provides most of the binding affinity for IFN and IFNAR1 is required for optimum signaling.

Citations

Documentation

Neutralization Effect of PBL Anti-Human IFNAR2 Monoclonal Antibody (21385) on Human IFN Alpha 2a (11100) and IFN Beta (11415) Activities in an A549 Cell/EMCV CPE Assay

 

Image depicting PBL Anti-Human IFNAR2 Monoclonal's neutralizing effect on Human IFN Alpha and IFN Beta protection of A549 cells from the cytopathic effect of EMCV infection
品牌介绍
来自PBL的iLite细胞基于常规的基因报告基因检测方法,并通过使用靶标特异性报告基因构建体进行工程改造。它们为定量测定生物活性干扰素水平提供了一种简单且经济高效的方法。