Human IFN Alpha 1 (Alpha D)

Product Features:

Human IFN Alpha 1 recombinant protein expressed in E.coli
Expression induced by viral infection
Encoding gene IFNA1 at position Ala¹¹⁴

Catalog No.	Pack Size	Price	Quantity
11175-1	1 x 10⁵ units	$280.00

Specifications
Tech Info / Data
Citations
Documentation

Specifications

Formulation	Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight	19.4 kDa
Source	cDNA obtained from human leukocyte mRNA expressed in E.coli
Purity	> 95% by SDS-PAGE stained by Coomassie BlueEndotoxin level < 1 EU/mg
Bioactivity	Measured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)
Storage	For retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles
Synonyms	Hu-[Ala¹¹⁴] IFN-αD
Accession Number	J00210

Tech Info / Data

Application Note:

A Comparison of the Binding of Interferon Alpha Subtypes to Isolated IFNAR1 and IFNAR2 with Activity in Antiviral and Antiproliferative Assays (link)

Background:

Recombinant Human Interferon Alpha 1 (Human alpha 1; Hu-[Ala¹¹⁴] IFN-alpha D) obtained from human leukocyte mRNA expressed in E.coli.

IFN alpha 1 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative and natural killer cell activities.