Mouse IFN Alpha 13

Product Features:

Recombinant Mouse IFN Alpha 13 protein expressed in E.coli
Member of the Mouse IFN alpha family which may be constitutively expressed and thus have different expression criteria than other subtypes

Catalog No.	Pack Size	Price	Quantity
12130-1	1 x 10⁵ units	$325.00

Specifications
Tech Info / Data
Citations
Documentation

Specifications

Formulation	Supplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight	19.1 kDa
Source	cDNA obtained from mouse leukocyte interferon expressed in E.coli
Purity	> 95% by SDS-PAGE stained by Coomassie BlueEndotoxin level < 1 EU/μg
Bioactivity	Measured using a cytopathic inhibition assay on Mouse (L929) cells with EMCV.The EC₅₀for IFN in this assay is ~ 5 U/ml.
Storage	For retention of full activity store at -70°C or below and avoid repeated freeze/thaw cycles
Synonyms	Mu IFN-α13, Mouse IFN Alpha Subtype, Mouse IFN Protein Subtype, Interferon Alpha, IFN Alpha, IFN-a, Type I IFN Alpha
Accession Number	AY220461

Tech Info / Data

Background:

Mouse IFN Alpha 13 was recently cloned from cells infected with Theiler"s virus [van Pesch and Michiels (2003) J. Biol. Chem., 278(47):46321] and from genomic DNA [Hardy et al. (2004) Genomics 84(2):331]. Van Pesch and Michiels had suggested that Mouse IFN Alpha 13 is expressed constitutively in L929 cells. They have also shown that priming of the cells with IFN alpha/beta leads to a decrease in this transcript.

Summary: Mouse IFN alpha 13 is a new interferon which may be constitutively expressed and thus have different expression criteria than other Mu IFN alpha subtypes.

For more information on Mouse IFN Alpha subtype nomenclature click here.